Our full list of publications can be found here:
Selected list of publications:
Simon S, Bugos G, Prins R, Rajan A, Palani A, Heyer K, Stevens A, Zeng L, Thompson K, Price JP, Kluesner MK, Jaeger-Ruckstuhl C, Shabaneh TB, Olson JM, Su X, Riddell SR. Design of sensitive monospecific and bispecific synthetic chimeric T cell receptors for cancer therapy. Nature Cancer. 6, 647–665 (2025). https://doi.org/10.1038/s43018-025-00927-0.
Cofey DG, Ataca Atilla P, Atilla E, Landgren O, Cowan AJ, Simon S, Pont MJ, Comstock ML, Hill GR, Riddell SR, Green DJ. Single-cell analysis of the multiple myeloma microenvironment after gamma-secretase inhibition and CAR T-cell therapy. Blood. 2024 Oct 7:blood.2024025231. doi: 10.1182/blood.2024025231.
Simon S, Bugos G, Riddell SR. Synthetic HLA-independent T cell receptors for cancer immunotherapy. Cancer Cell. 2022 Apr 11;40(4):359-361.
Simon S, Bugos G, Salter AI, Riddell SR. Synthetic receptors for logic gated T cell recognition and function. Curr Opin Immunol. 2022 Feb;74:9-17.
Simon S, Voillet V, Vignard V, Wu Z, Dabrowski C, Jouand N, Beauvais T, Khammari A, Braudeau C, Josien R, Adotevi O, Laheurte C, Aubin F, Nardin C, Rulli S, Gottardo R, Ramchurren N, Cheever M, Fling SP, Church CD, Nghiem P, Dreno B, Riddell SR, Labarriere N. PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy. J Immunother Cancer. 2020 Nov;8(2):e001631.
Simon S, Riddell SR. Dual Targeting with CAR T Cells to Limit Antigen Escape in Multiple Myeloma. Blood Cancer Discov. 2020 Aug 3;1(2):130-133.
Simon S, Vignard V, Varey E, Parrot T, Knol AC, Khammari A, Gervois N, Lang F, Dreno B, Labarriere N. Emergence of high avidity Melan-A specific clonotypes as a reflection of anti-PD-1 clinical efficacy. Cancer Res. 2017. (77) (24) 7083-7093; DOI:10.1158/0008-5472.
Simon S, and Labarriere N. PD-1 expression on tumor-specific T cells : Friend or Foe for immunotherapy ? OncoImmunology. 2017. DOI: 10.1080/2162402X.2017.1364828.
Simon S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, Labarriere N. PD-1 expression conditions T cell avidity within an antigen-specific repertoire. OncoImmunology. 2015 Oct 29 ;5(1):e1104448.
